Injection may reduce fatigue…

Patients with fibromyalgia may have improvements in fatigue and musculoskeletal pain by increasing vitamin D levels through monthly, intramuscular cholecalciferol injection, according to recently presented research.

A study of 73 patients with rheumatoid arthritis (RA), 102 patients with osteoarthritis (OA) and 40 patients with fibromyalgia (FM) who did not supplement with vitamin D was conducted. Baseline vitamin D levels were measured, and a VAS was used to assess musculoskeletal pain and fatigue. Patients received 200,000 IU cholecalciferol every 4 weeks through an intramuscular injection for a total of three injections during the study period. VAS and biochemical response were measured at baseline, 12 and 24 weeks.

Patients with FM (77.5%) had significantly lower levels of vitamin D compared with patients with RA (64.4%) and OA (23.5%) at baseline. Levels of vitamin D were negatively correlated with VAS for pain and fatigue in all three diseases, but also with the Disease Activity Score in 28 joints in patients with RA and with the Fibromyalgia Impact Questionnaire (FIQ) score in patients with FM.

At week 12, mean serum 25-OHD levels were significantly higher in the 102 patients with 25-OHD deficiency at baseline. After receiving cholecalciferol injections, patients from each group showed significant decreases from baseline in VAS for pain and fatigue at weeks 12 and 24; however, the effects were greater in patients with FM compared with patients with RA or OA between weeks 12 and 24, according to the researchers. – by Shirley Pulawski


Choi BY, et al. Paper #THU0307. Presented at: European League Against Rheumatism Annual European Congress of Rheumatology; June 10-13, 2015; Rome.


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This is a blog for all Fibromyalgia sufferers. I have fibromyalgia myself. I blog about my fibro health and life. The problems I have with Fibromyalgia and how I solve them. I write about therapies, medications and the life itself, as a disabled person who wants to be thought of as normal. I have two children, they both live at home with me. Both boys they are 22 and 18 years of age. I also have at home three dogs and two cats. Yes, sometimes it’s like a zoo around here. I live in California. I am surviving on Social Security Disability Insurance and marketing online. It has been slow going but I am making it work. I am no longer able to work outside the home because of the fibromyalgia. I used to be a Loan Officer for a large mortgage company. I also have a Real Estate license. I use to be a very busy person. The fibromyalgia has taken a lot out of me. As I am sure it has for you too. So I write for you, the hurting and disabled with Fibromyalgia, Chronic Fatigue, IBS, and all the other symptoms we so boldly carry. My hope is that you’ll get some value out of this blog. Always feel as if you can comment on my views. I would love to hear some interaction from my readers. I have created the site to truly help people that are experiencing difficulty in their own lives with Fibromyalgia. Many people in America and all over the world are suffering from this disease. This site is dedicated to helping provide the most up to date information about living and coping with Fibromyalgia in your everyday life. I am not a doctor, nor am I licensed to give medical advice in any way. Any information you find on my blog is strictly an opinion and should not be taken as medical advice. You are responsible for any information you use from this site in your own life. Please talk with a licensed, medical professional before making any important decisions about your health or illness. Thank you. Sincerely, April Baldner (myfibrolife)